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Azel Zine

University of Montpellier, France

Biography

Azel Zine has his expertise in the study of development and regeneration of the peripheral auditory system. He has made seminal contributions to our understanding of the Notch signaling and HES gene roles in the development of auditory hair cells in mammals. His scientific contributions have all been well thought out and comprehensive, published in some of highly peer reviewed journals. His work with applying the degradation resistant JNK inhibitor (D-JNK-1) to the inner ear as an otoprotective drug has also been notable and the results reported in that initial work has led to clinical trials in Europe that are in progress under the direction of Auris Medical-Biotechnology Company. His current research is in the field of stem cells biology.

Abstract

Abstract : Migration, integration and differentiation of human induced pluripotent stem cell-derived otic progenitors following transplantation in animal model of sensorineural hearing loss