Stem Cell Niches

The anatomical region where stem cells are found in a shallow recess is referred to a stem-cell niche. It refers to a microenvironment with reference to the in vivo or in vitro stem cells; they even interact with stem cells to regulate cell fate. Various niche factors act on embryonic stem cells to induce their proliferation or differentiation for the development of the fetus and in altering the gene expression during the embryonic development. In the human body, stem cells maintain the adult stem cells in a dormancy state, but during the tissue injury it actively signals to stem cells to promote either self-renewal or differentiation to form a new tissue

  • GSC niche in drosophila ovaries
  • Molecular mechanism of GSC
  • Vertebrate adult stem cell niche
  • Extracellular matrix mimicking strategies
  • Atrial cardiac stem cells niche

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